Welcome to Astarte Biologics, the best place to purchase human or murine immune cells. We characterize our blood donors and purified cells so you can be sure of the quality of the cells you purchase. All PBMC are tested for recall antigen responses; purified cell types are checked by flow cytometric analysis for enrichment of the desired cell type. Many of our donors are HLA typed. All donors are tested for blood borne pathogens and must be negative for these infections in order to participate. Donors have given informed consent and our collection protocol has been reviewed by an accredited Investigational Review Board for compliance with international standards of human research.
In addition to our cell products we have reagents for inflammation research. Our Rheumera® kits measure type II collagen, proteoglycans and autoantibodies to type II collagen. Also our HUVEC E-Selectin kit measures expression of E-Selectin on endothelial cells.
Our lipopolysaccharides are characterized too. These bind to specific toll-like receptors (TLR) and are great tools for investigating the role of TLR in immunity and inflammation.
Browse our listing of cell types and come back often as we add new products and new protocols. Don't hesitate to contact us via phone or the contact page. We look forward to working with you.
New Cell Type
We now offer several immortalized B cell lines. These are derived from our donors by infecting peripheral blood mononuclear cells with Epstein-Barr virus. The EBV transformed B lymphoblastoid cell lines (B-LCL) can be used as antigen presenting cells and are a convenient alternative to PBMC for that purpose. Donor 3 B-LCL can be used to maintain the BC3 T cell line derived from the same donor. They are listed along with our primary human B cells on the B cell page.
Astarte Biologics has mouse cells to match its human cell inventory. Mouse bone marrow cells, spleen cells, macrophages and dendritic cells come with flow cytometric analysis data and are ready to use.
Purified T cells are available from Astarte Biologics. We have CD3+ cells as well as CD4+ and CD8+ subsets. Purity is confirmed by flow cytometric analysis.
Phagocytosis of yeast by human monocytes. Monocytes are stained with Alexa Fluor 488-phalloidin (green) and yeast are labeled with AlexaFluor 594 (red). For experimental details, click here. Alexa Fluor® is a trademark of Molecular Probes, Inc.
Astarte Biologics has PBMC and plasma from individuals with with a variety of autoimmune diseases including SLE, rheumatoid arthritis, ankylosing spondylitis and multiple sclerosis.