Natural Killer Cells (NK cells) are important effector cells in combating viral infections and neoplasms. Their cytotoxic activity is controlled by multiple receptors that recognize MHC class I antigens. Cells that lack the appropriate MHC class I are lysed because the inhibitory receptor is not engaged. For further information see the review articles listed below.

Our NK cells are isolated by negative immunomagnetic selection. To see cell count, viability and flow cytometric analysis of each lot, click on the links in the table.

NK Cell Review articles

Moretta A, Bottino C, Vitale M, Pende D, Cantoni C, Mingari MC, Biassoni R, Moretta L. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu Rev Immunol. 2001;19:197-223.Abstract at Annual Reviews

Carayannopoulos LN, Yokoyama WM. Recognition of infected cells by natural killer cells. Curr Opin Immunol. 2004 Feb;16(1):26-33. Abstract at Science Direct

Cheent K, Khakoo SI. Natural killer cells: integrating diversity with function. Immunology. 2009 Apr;126(4):449-57. Abstract at Wiley

Apologies to the many contributors to this field who are not listed.